The OCCAMS study
Oesophageal and junctional adenocarcinomas (OAC) have a poor prognosis and the standard of care is cytotoxic chemotherapy with or without radiotherapy followed by surgery. In contrast to other cancers, as yet knowledge of the molecular pathogenesis of the disease has not been used to determine prognosis and therapy.
The OCCAMS (Oesophageal Cancer Clinical and Molecular Stratification) study is a network of clinical centres recruiting OAC patients for tissue collection. OAC patient data and tissue samples are used to attempt to identify clinical, demographic and molecular factors affecting disease progression.